GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs1875620 | 1 | rs7020528 | chr9:91564761 | C9orf47 | chr9:91605778-91611055:+ | -0.26 | -4.42 | 2.59E-5 | Response to statins (LDL cholesterol change) |
| THYM | cis | rs7849270 | 1 | rs7020708 | chr9:131885131 | CRAT | chr9:131857075-131873070:- | 0.38 | 4.61 | 1.24E-5 | Blood metabolite ratios |
| THYM | cis | rs7849270 | 1 | rs7021449 | chr9:131899312 | CRAT | chr9:131857075-131873070:- | 0.42 | 4.98 | 2.82E-6 | Blood metabolite ratios |
| THYM | cis | rs1875620 | 1 | rs7021651 | chr9:91548799 | C9orf47 | chr9:91605778-91611055:+ | -0.27 | -4.75 | 7.31E-6 | Response to statins (LDL cholesterol change) |
| THYM | cis | rs6477998 | 1 | rs7022397 | chr9:116007677 | CDC26 | chr9:116029290-116037869:- | -0.36 | -5.77 | 9.96E-8 | Hematology traits |
| THYM | cis | rs7849270 | 1 | rs7023900 | chr9:131891152 | CRAT | chr9:131857075-131873070:- | 0.42 | 4.98 | 2.82E-6 | Blood metabolite ratios |
| THYM | cis | rs1875620 | 1 | rs7024847 | chr9:91565755 | C9orf47 | chr9:91605778-91611055:+ | -0.26 | -4.42 | 2.59E-5 | Response to statins (LDL cholesterol change) |
| THYM | cis | rs1875620 | 1 | rs7028197 | chr9:91555066 | C9orf47 | chr9:91605778-91611055:+ | -0.26 | -4.68 | 9.7E-6 | Response to statins (LDL cholesterol change) |
| THYM | cis | rs1875620 | 1 | rs7032526 | chr9:91564276 | C9orf47 | chr9:91605778-91611055:+ | -0.27 | -4.71 | 8.28E-6 | Response to statins (LDL cholesterol change) |
| THYM | cis | rs1875620 | 1 | rs7032662 | chr9:91564355 | C9orf47 | chr9:91605778-91611055:+ | -0.27 | -4.71 | 8.28E-6 | Response to statins (LDL cholesterol change) |
| THYM | cis | rs7849270 | 1 | rs7036114 | chr9:131893406 | CRAT | chr9:131857075-131873070:- | 0.42 | 4.98 | 2.82E-6 | Blood metabolite ratios |
| THYM | cis | rs7849270 | 1 | rs7036236 | chr9:131899299 | CRAT | chr9:131857075-131873070:- | 0.38 | 4.61 | 1.24E-5 | Blood metabolite ratios |
| THYM | cis | rs881375 | 1 | rs7037140 | chr9:123656327 | LOC253039 | chr9:123605320-123616644:+ | -0.62 | -5.56 | 2.51E-7 | Rheumatoid arthritis |
| THYM | cis | rs7849270 | 1 | rs7037163 | chr9:131894340 | CRAT | chr9:131857075-131873070:- | 0.47 | 5.4 | 4.92E-7 | Blood metabolite ratios |
| THYM | cis | rs1875620 | 1 | rs7037603 | chr9:91565874 | C9orf47 | chr9:91605778-91611055:+ | -0.26 | -4.45 | 2.34E-5 | Response to statins (LDL cholesterol change) |